TOP-5 studies on obesity, diabetes, and insulin resistance from May 13, 2026, to May 20, 2026.
Innovations in obesity treatment: beyond adipose tissue dysfunction; Optimizing adherence and outcomes: potential strategies for enhancing the effectiveness of nutrient-stimulated hormonal therapy; Misclassification of type 1 diabetes as type 2 diabetes in adults: a practical guide for screening and diagnosis for primary care physicians; Metarnil in diabetes and its complications: conflicting data and prospects for translation; Ultra-processed foods and cardiovascular health risks: a review of current data, recommendations, and statements.
5. Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction.
About the work.
Obesity is discussed as a multisystem disease with metabolic, immunological, and oncological aspects. Innovative therapeutic strategies for treating obesity and related diseases are considered.
Results.
The available abstract does not describe the results in sufficient detail.
4. Optimizing Adherence and Outcomes: Potential Strategies to Enhance the Effectiveness of Nutrient-Supported Hormonal Therapy.
About the work.
The review aims to optimize clinical outcomes of nutrient-supported therapy in managing obesity and type 2 diabetes. Strategies aimed at improving adherence and treatment outcomes are discussed.
Results.
Preclinical studies show that NuSH therapies alter gut microbiota towards "lean-associated" profiles. However, data on humans remain limited and heterogeneous. Structured support in nutrition and behavior is necessary to ensure nutrient adequacy and manage side effects.
3. Misclassification of Type 1 Diabetes as Type 2 Diabetes in Adults: A Practical Guide for Screening and Diagnosis for Primary Care Physicians.
About the work.
The study addresses the issue of misclassification of type 1 diabetes (T1D) in adults, focusing on clinical signs that aid in its identification. Cases are discussed that highlight the importance of accurate diagnosis to prevent complications.
Results.
The available abstract does not describe the results in sufficient detail.
2. Metrnl in Diabetes and Its Complications: Contradictory Data and Prospects for Translation.
About the work.
The review explores the role of the protein Metrnl in diabetes and its complications, analyzing existing data on its expression and functions. Results from preclinical and clinical studies are compared.
Results.
Metrnl improves insulin sensitivity, protects pancreatic β-cells, and reduces diabetes-related damage in the kidneys, heart, and skin. However, clinical data on Metrnl levels in patients with type 2 diabetes are contradictory, with reports of decreases, increases, or no significant changes.
1. Ultra-Processed Foods and Cardiovascular Health Risks: A Review of Current Evidence, Recommendations, and Statements.
About the work.
The review presents current data on the association between the consumption of ultra-processed foods and cardiovascular diseases, as well as the positions of major scientific organizations on this issue.