TOP-5 Studies on Nutrients and Orthomolecular Medicine from 15.05.2026 - 22.05.2026
Calcium, vitamin D, or a combined supplement for the prevention of fractures and falls: a systematic review and meta-analysis; GLP-1 receptor agonists and surgical treatment: implications for bariatric procedures, perioperative outcomes, and nutritional optimization; Healing from within: vitamins and nutritional strategies for complex regional pain syndrome and chronic postoperative pain; Diet and acne: facts and controversies; Nutrition and pharmacological support to meet metabolic needs after trauma: a narrative review.
5. Calcium, vitamin D, or a combined supplement for the prevention of fractures and falls: a systematic review and meta-analysis.
About the work.
The aim of the study was to evaluate the impact of calcium, vitamin D, or their combination on the risk of fractures and falls in adults. Data from randomized controlled trials were analyzed in the systematic review and meta-analysis.
Results.
remained stable after heterogeneity analysis in several subgroups.
4. GLP-1 receptor agonists and surgical treatment: implications for bariatric procedures, perioperative outcomes, and nutritional optimization.
About the work.
The study focuses on the impact of glucagon-like peptide-1 receptor agonists (GLP-1RA) on patient management in the perioperative period, outcomes of bariatric surgery, and nutritional optimization. The effects of GLP-1RA on the safety of surgeries and intervention outcomes are discussed.
Results.
Use of GLP-1RA is associated with delayed gastric emptying and increased gastric residual volume in some patients; however, clinically significant aspiration events were rare. Preoperatively, GLP-1RA contributed to short-term weight loss and improved metabolism in candidates for bariatric surgery.
3. Healing from within: vitamins and nutritional strategies for complex regional pain syndrome and chronic postoperative pain.
About the work.
This literature review evaluates the impact of vitamins on complex regional pain syndrome (CRPS) and chronic postoperative pain (CPSP). Data on the potential benefits of vitamin therapy for patients with these conditions are discussed.
Results.
Data indicate a significant role of systemic vitamin C in preventing CRPS after various orthopedic surgeries and potential therapeutic benefits. Vitamin B12 improved short-term functional and mental outcomes and reduced the need for neuropathic analgesics. Preclinical studies suggest that alpha-lipoic acid may reduce cold allodynia and pain in mice.
2. Diet and acne: facts and controversies.
About the work.
The influence of diet and nutrition on the pathogenesis of acne is examined, focusing on various types of diets and their association with the disease. Observed associations between acne and high glycemic loads, dairy products, and the omega-6/omega-3 fatty acid ratio are discussed.
Results.
The available abstract does not describe the results in sufficient detail.