TOP-5 studies on disease treatment from 09.08.2026 - 16.08.2026

Ketogenic effects of medium-chain triglycerides coated with milk protein in healthy men: a randomized, double-blind, crossover study; Effectiveness of wearable device-based interventions to improve depression, anxiety, stress, and quality of life in adults: a systematic review and meta-analysis; Analysis of the sensitive period of body mass index in adulthood and cancer risk: a meta-analysis of individual participant data from over 720,000 participants in the ABACus 2 consortium; Impact of short-term reduction of hepatic triglycerides on vascular health in adults with metabolic dysfunction associated with fatty liver or at risk; Metabolic revolution in dermatology: obesity, insulin resistance, and ultra-processed diets as factors in skin inflammation.
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5. Effectiveness of wearable device-based interventions to improve depression, anxiety, stress, and quality of life in adults: a systematic review and meta-analysis.

Type: Systematic review / meta-analysis
Source: PubMed

About the study.
The aim of the study was to systematically examine the impact of interventions using wearable devices on depression, anxiety, stress, and quality of life in adults. The study included randomized controlled trials comparing these interventions with control conditions.

Results.
Wearable devices were associated with improvements in depression (SMD = -0.43), anxiety (SMD = -0.49), and quality of life (SMD = 0.41). Subgroup analyses showed more pronounced effects on depression among studies conducted in Europe and among participants with metabolic disorders.

4. Ketogenic effects of medium-chain triglycerides coated with milk protein in healthy men: a randomized, double-blind, crossover study.

Type: Randomized controlled trial
Source: PubMed

About the study.
The study aimed to evaluate the ketogenic effects of medium-chain triglyceride microparticles coated with milk protein in healthy men. Blood ketone levels were compared after the intake of coated and uncoated MCTs.

Results.
The maximum concentration changes in ketone bodies, β-hydroxybutyrate, acetoacetate, and octanoic acid were significantly higher in the group taking coated MCTs compared to uncoated.

3. Analysis of the sensitive period of body mass index in adulthood and cancer risk: a meta-analysis of individual participant data from over 720,000 participants in the ABACus 2 consortium.

Type: Systematic review / meta-analysis
Source: PubMed

About the study.
The study aimed to analyze the impact of body mass index (BMI) on cancer risk at different age periods of adult life. Data from over 720,000 participants were used to identify sensitive age periods for cancer risk associated with obesity.

Results.
Positive associations between BMI and obesity-related cancer were found at ages 30-65. In women aged 35 and 40, interactions with obesity-related cancer risk were identified, with HR 1.04 and 1.05 respectively. Higher BMI increased the risk of obesity-related cancer throughout adult life.

2. Impact of short-term reduction of hepatic triglycerides on vascular health in adults with metabolic dysfunction associated with fatty liver or at risk.

Type: Randomized controlled trial
Source: PubMed

About the study.
The study aimed to evaluate the impact of short-term reduction of triglycerides in the liver on vascular health in adults with metabolic syndrome. Participants were divided into two groups and subjected to dietary intervention.


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