Combination of B-Complex Vitamins and Magnesium Improves Cognitive Functions and Reduces Anxiety — Clinical Study Results

Recent clinical studies demonstrate that the combined intake of B vitamins and magnesium positively affects cognitive functions and emotional well-being in adults experiencing a deficiency of these essential micronutrients.

B vitamins (including B1, B5, B6, B12, and folic acid) play a critical role in brain metabolism, supporting neurotransmitters and eliminating toxic metabolites such as homocysteine, the levels of which are directly linked to cognitive impairments and an increased risk of depression.

Magnesium is involved in hundreds of enzymatic reactions, supports nerve signal transmission, and helps regulate emotional states due to its calming effect and role in memory formation.

Key Findings of the Studies

• The combined intake of B-complex vitamins and magnesium contributes to improved memory, attention, and overall cognitive functioning.
• A reduction in anxiety levels and improvement in sleep quality were noted in individuals taking these micronutrients.
• Optimal supply of these substances to the brain supports the synthesis of neurotransmitters such as acetylcholine and serotonin, which is important for the prevention of depression and cognitive decline.
• Deficiencies in B vitamins and magnesium are often accompanied by memory and mood disturbances, and their replenishment may slow the progression of age-related cognitive impairments and dementia.

Orthomolecular medicine suggests using such combinations of vitamins and minerals to create an optimal biochemical environment in the brain for the prevention and additional support in cognitive and psycho-emotional disorders.

It should be emphasized that the orthomolecular approach is not a cure for neurological diseases; however, it can enhance quality of life, alleviate symptoms, and slow the deterioration of cognitive functions.

Clinical data confirm the effectiveness of the combined intake of B vitamins and magnesium, making their use a promising direction in the prevention of cognitive impairments and improvement of mental health.