TOP-5 studies on biohacking and longevity from 26.06.2026 - 03.07.2026
Management of colorectal sessile serrated lesions in elderly patients; Social determinants of health in mental disorders: promising opportunities for biopsychosocial research and clinical practice; Shedding light on aging processes through multimodal optical metabolic imaging; Circadian rhythm: the hidden "puppet master" behind musculoskeletal disorders; Pachymic acid alleviates circadian rhythm disorders.
5. Management of colorectal sessile serrated lesions in elderly patients.
About the work.
Management of sessile serrated lesions (SSL) of the colon in elderly patients is considered, taking into account the unique risks and characteristics of this group. The complexities of clinical decision-making due to comorbidities and age factors are discussed.
Results.
The available abstract describes the results inadequately.
4. Social determinants of health in mental disorders: promising opportunities for biopsychosocial research and clinical practice.
About the work.
Social determinants of health are discussed as important factors influencing mental disorders. The mechanisms through which these determinants affect mental health are examined.
Results.
Social factors such as social connection significantly impact overall health and longevity. Loneliness and social isolation have become serious global public health issues. A biopsychosocial model is proposed for understanding the risk and prevention of mental illnesses.
3. Shedding light on aging processes through multimodal optical metabolic imaging.
About the work.
The review discusses recent advances in metabolic imaging, particularly using multimodal nonlinear optical methods applied to the study of aging biology.
Results.
Optical metabolic imaging provides unique data on the mechanisms of aging, capturing metabolic changes from organelle-level interactions to tissue remodeling.
2. Circadian rhythm: the hidden "puppet master" behind musculoskeletal disorders.
About the work.
The influence of circadian rhythm on the physiology of the musculoskeletal system and the mechanisms through which its disruption may contribute to disease development are considered. Possible interventions for treating these diseases, taking circadian rhythm into account, are also discussed.
Results.
The available abstract describes the results inadequately.
1. Pachymic acid alleviates circadian rhythm disorders in diet-induced obese mice through the sphingolipid pathway.
About the work.
The study aims to evaluate the effect of pachymic acid on circadian rhythm disorders in mice with obesity induced by a high-fat diet. Metabolic parameters and circadian parameters were compared.








