TOP-5 studies on nutrients and orthomolecular medicine from 24.09.2026 - 01.10.2026
Low prevalence of research biochemical patterns compatible with osteomalacia in a large cohort of participants with low serum 25-hydroxyvitamin D; Combined use of calcium and multi-component micronutrient supplements to assess hemoglobin and iron in mothers and newborns: a protocol for a randomized non-inferiority trial in Burkina Faso and Pakistan; Nutritional vulnerabilities and dietary differences among migrants in the informal sector: a global review; Vitamin D deficiency exacerbates diabetic peripheral neuropathy, while supplementation alleviates neuropathic pain; Addition of polyunsaturated fatty acids (PUFAs) and outcomes in ADHD in children and adolescents: a systematic review and meta-analysis of randomized controlled trials.
5. Low prevalence of research biochemical patterns compatible with osteomalacia in a large cohort of participants with low serum 25-hydroxyvitamin D.
About the work.
The study aims to assess the prevalence of biochemical patterns compatible with osteomalacia in a population with low vitamin D levels, as well as the impact of vitamin D supplementation on biochemical parameters. Participants were recruited from the Tromsø population study.
Results.
None of the participants had a combination of high parathyroid hormone and alkaline phosphatase levels with low calcium levels. The prevalence was 8.3% for the most permissive biochemical pattern. During the intervention, vitamin D significantly reduced parathyroid hormone and alkaline phosphatase levels and increased serum calcium levels compared to placebo.
4. Combined use of calcium and multi-component micronutrient supplements to assess hemoglobin and iron in mothers and newborns: a protocol for a randomized non-inferiority trial in Burkina Faso and Pakistan.
About the work.
The study aims to evaluate whether the combined use of calcium and multi-component supplements (CaMMS) is no worse than separate intake for the status of hemoglobin and iron in pregnant women. The study involves 1600 women in Burkina Faso and Pakistan.
Results.
The available abstract does not describe the results in sufficient detail.
3. Nutritional vulnerabilities and dietary differences among migrants in the informal sector: a global review.
About the work.
The review aims to study the nutritional status and structural factors influencing vulnerability to malnutrition among migrants working in informal sectors. The study covers 59 studies identified from 1,275 records.
Results.
A high level of malnutrition was identified, including wasting, underweight, and stunting, especially among children. Common conditions related to micronutrient deficiencies include anemia and vitamin D deficiency. A dual burden of malnutrition, including overweight and obesity, was noted. Key vulnerability factors include food security, low wages, unstable working conditions, and gender vulnerabilities.
2. Vitamin D deficiency exacerbates diabetic peripheral neuropathy, while supplementation alleviates neuropathic pain.
About the work.
The study aims to assess the relationship between vitamin D deficiency and diabetic peripheral neuropathy (DPN), as well as to explore the impact of vitamin D supplementation on neurological outcomes. Observational and interventional studies comparing vitamin D levels in diabetics with and without DPN were included.