TOP-5 studies on disease treatment from 13.09.2026 - 20.09.2026
Risk factors for frailty in older adults with cancer; The effect of fish oil as an adjunct therapy to metformin on vascular and heart health in women with polyendocrine metabolic syndrome of the ovaries: a protocol for a randomized, placebo-controlled clinical trial; Hepatic steatosis: a pandemic disease causing serious comorbidities; Plant-based diets, cognitive functions, and Alzheimer's disease; Mechanistic link between obesity, depression, and cognitive decline in Alzheimer's disease.
5. Risk factors for frailty in older adults with cancer: a systematic review.
About the work.
The aim of the study was to identify risk factors for frailty in older adults with cancer through a systematic review of existing data. The study included 30 publications covering both correlational and predictive factors of frailty.
Results.
Factors influencing frailty were divided into six categories: disease-related, physiological, psychological, lifestyle, sociodemographic, and treatment-related.
4. The effect of fish oil as an adjunct therapy to metformin on vascular and heart health in women with polyendocrine metabolic ovarian syndrome: a protocol for a randomized, placebo-controlled clinical trial.
About the work.
The aim of this study is to evaluate the effectiveness of fish oil as an adjunct therapy to metformin for reducing triglyceride and apoB-lipoprotein levels in women with polyendocrine metabolic syndrome of the ovaries. The study will be conducted as a randomized controlled clinical trial.
Results.
The available abstract does not describe the results in sufficient detail.
3. Hepatic steatosis: a pandemic disease causing serious comorbidities.
About the work.
The study focuses on the prevalence and consequences of fatty liver disease, known as MASLD, and its more dangerous form MASH. It examines the associations of these diseases with various comorbid conditions and risks.
Results.
Conditions associated with MASLD and/or MASH include obesity, dyslipidemia, hypertension, type 2 diabetes, obstructive sleep apnea, cardiovascular diseases, and chronic kidney disease. The frequency of serious secondary diseases increases with the progression of fibrosis, and cardiovascular events are the leading cause of death.
2. Plant-based diets, cognitive functions, and Alzheimer's disease.
About the work.
The review explores the relationship between plant-based diets and cognitive decline and the risk of Alzheimer's disease, analyzing data from observational and interventional studies of various dietary patterns.
Results.
Long-term observational studies show that greater adherence to vegan, vegetarian, and healthy plant-based diet indices is associated with a lower risk of cognitive decline and dementia. Pesco-vegetarian diets and increased fish consumption may improve memory test outcomes and reduce the risk of dementia.