TOP-5 studies on keto, low-carbohydrate diets, and intermittent fasting from 19.10.2026 - 26.10.2026
The impact of maternal diet on the metabolic health of mothers and offspring; Astrocytic ketogenesis protects the central nervous system from damage; Dietary context and ethanol-associated injury in preclinical models: a contemporary systematic review of predominantly obesogenic diets and liver outcomes; Metabolic diets and fasting in oncology: integrating recommendation-based nutrition, nutrition assessments, and clinical pathology driven by biomarkers; Dynamics of lipids and cardiovascular risk profiles in carbohydrate- or saturated fat-based diets: a secondary analysis of the CARBFUNC trial.
5. Dietary context and ethanol-associated injuries in preclinical models: a contemporary systematic review of predominantly obesogenic diets and liver outcomes.
About the work.
Aimed at studying the impact of various dietary patterns on ethanol-induced liver injury in controlled preclinical models. Primarily high-fat and Western diets were considered in comparison to ethanol.
Results.
High-fat and Western diets generally exacerbated ethanol-induced liver injury. In acute high-fat models, ethanol addition increased ALT, AST, and triglyceride levels in the liver. In acute interaction analysis, diet modified the effect only for ALT, while chronic analyses showed a negative interaction for liver triglycerides.
4. Metabolic diets and fasting in oncology: integrating recommendation-based nutrition, nutrition assessments, and clinical pathology driven by biomarkers.
About the work.
The review focuses on the integration of oncology nutrition recommendations, experimental metabolic diets, and clinical pathology based on biomarkers. Various approaches to nutrition and fasting in the context of oncology are discussed.
Results.
Clinical studies show that fasting-related regimens and ketogenic diets may improve certain metabolic, hematological, quality of life, and pathological endpoints in carefully selected patients, but reproducible survival benefits have not been established.
3. Dynamics of lipids and cardiovascular risk profiles in carbohydrate- or saturated fat-based diets: a secondary analysis of the CARBFUNC trial.
About the work.
The study aimed to assess the impact of high and low carbohydrate and fat diets on lipid profiles and cardiovascular disease risk in obese individuals. The effects of an accelerated carbohydrate diet, a cellular carbohydrate diet, and a low-carbohydrate high-fat diet were compared.
Results.
The LCHF group showed significant reductions in very low-density lipoprotein levels, triglycerides, residual cholesterol, and the triglyceride to high-density lipoprotein cholesterol ratio in the first 9-12 months compared to other diets, as well as an increase in high-density lipoprotein cholesterol and total apolipoprotein A1 levels.
2. The impact of maternal ketogenic diet on the metabolic health of mothers and offspring in mice.
About the work.
The study aimed to evaluate the impact of maternal ketogenic diet on the metabolic health of both mothers and their offspring in mice. Metabolic status indicators were compared between females on ketogenic and control diets.