Jack Challem, Feed Your Genes Right: Eat to Turn Off Disease-Causing Genes and Slow Down Aging (2005)

The book explains the principles of nutrigenomics in an accessible way: diet and lifestyle can “switch off” genes that increase the risk of chronic diseases and slow down aging by creating a favorable nutritional environment for DNA — more whole, nutrient-dense foods and fewer refined carbohydrates and sugars.

The key mechanisms are methylation and DNA protection: B-vitamins (folate, B6, B12, along with choline and betaine) support DNA synthesis and repair and lower homocysteine levels, while excess sugar and certain cooking methods damage DNA and accelerate aging.

The author offers practical conclusions: the diet should be based on fish, vegetables, and berries; antioxidants (vitamins E and C), selenium, and coenzyme Q10 protect DNA and regulate gene activity; limiting “empty” carbohydrates and maintaining moderate physical activity enhance these effects.

Conclusion: genetic “predisposition” is not a sentence — through nutrition and supplementation one can reduce the risk of cardiovascular, neur...
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