TOP-5 Studies on Biohacking and Longevity from 03.07.2026 - 10.07.2026
Management of colorectal sessile serrated lesions in elderly patients; Social determinants of health in mental disorders: new opportunities for biopsychosocial research and clinical practice; Shedding light on aging processes through multimodal optical metabolic imaging; Circadian rhythm: the hidden "puppet master" behind musculoskeletal disorders; Pachymic acid alleviates circadian rhythm disorders.
5. Management of colorectal sessile serrated lesions in elderly patients.
About the work.
Management of sessile serrated lesions (SSL) of the colon in elderly patients is discussed, considering the unique risks and characteristics of this group. The complexities of clinical decision-making due to comorbidities and age factors are addressed.
Results.
The available abstract describes the results insufficiently in detail.
4. Social determinants of health in mental disorders: promising opportunities for biopsychosocial research and clinical practice.
About the work.
Social determinants of health are considered important factors influencing mental disorders. The mechanisms through which these determinants affect mental health are discussed.
Results.
Social factors such as social connection have a significant impact on overall health and longevity. Loneliness and social isolation have become serious global public health issues. A biopsychosocial model is proposed for understanding the risk and prevention of mental illnesses.
3. Shedding light on aging processes through multimodal optical metabolic imaging.
About the work.
The review discusses recent advancements in metabolic imaging, particularly using multimodal nonlinear optical methods applied to study the biology of aging.
Results.
Optical metabolic imaging provides unique data on the mechanisms of aging, capturing metabolic changes from interactions at the organelle level to tissue remodeling.
2. Circadian rhythm: the hidden "puppet master" behind musculoskeletal disorders.
About the work.
The influence of circadian rhythm on the physiology of the musculoskeletal system and the mechanisms through which its disruption may contribute to disease development are discussed. Possible interventions for treating these diseases considering circadian rhythm are also addressed.
Results.
The available abstract describes the results insufficiently in detail.
1. Pachymic acid alleviates circadian rhythm disorders in mice with diet-induced obesity through the sphingolipid pathway.
About the work.
The study aims to assess the impact of pachymic acid on circadian rhythm disorders in mice with obesity induced by a high-fat diet. Metabolic parameters and circadian parameters were compared.








