TOP-5 studies on disease treatment from 26.07.2026 - 02.08.2026
Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: a systematic review of clinical data; Effectiveness of mindfulness-based interventions on psychological stress, hyperandrogenism, and metabolic profile in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials; Does the addition of vitamin D modulate metabolic risk factors for cardiovascular disease? A systematic review and meta-analysis of clinical trials; Endocrine-disrupting chemicals associated with metabolic dysfunction and liver steatosis; The impact of a fasting-mimicking diet on cardiac structure and function assessed by MRI in participants with type 2 diabetes.
5. Effectiveness of mindfulness-based interventions on psychological stress, hyperandrogenism, and metabolic profile in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
About the work.
The aim of this study was to systematically assess the effectiveness of mindfulness interventions in women with polycystic ovary syndrome. The study compared anthropometric indices, metabolic profiles, and quality of life.
Results.
Women in the mindfulness intervention groups showed significant reductions in BMI, body weight, and waist circumference, as well as preliminary improvements in insulin resistance. Levels of total testosterone and clinical hirsutism also improved. Specific quality of life significantly improved, despite no significant changes in overall depression and anxiety scores.
4. Does the addition of vitamin D modulate metabolic risk factors for cardiovascular disease? A systematic review and meta-analysis of clinical trials.
About the work.
The study evaluated the impact of vitamin D supplementation on cardiometabolic risk factors such as lipid profile, blood pressure, and glycemic parameters, focusing on age and blood vitamin D levels.
Results.
Vitamin D significantly reduced LDL cholesterol by 0.136 mmol/L, systolic blood pressure by 2.79 mmHg, fasting glucose by 0.11 mmol/L, and hemoglobin A1c by 0.164% compared to placebo. Participants over 55 years showed reductions in systolic blood pressure and LDL cholesterol levels.
3. Endocrine-disrupting chemicals and their association with metabolic dysfunction and liver steatosis.
About the work.
The study aimed to assess the quantitative relationship between exposure to endocrine-disrupting chemicals (EDCs) and the prevalence of metabolic dysfunction associated with liver steatosis (MASLD). The systematic review and meta-analysis analyzed data from 42 studies covering various global populations.
Results.
The meta-analysis showed that certain phthalates, such as MECPP, MEHHP, and MBzP, are associated with increased rates of metabolic dysfunction related to liver steatosis.
2. Metabolic, adherence, and sustainability outcomes of plant-based low-carbohydrate and ketogenic diets: a systematic review of clinical data.
About the work.
The study aimed to evaluate the impact of plant-based low-carbohydrate and ketogenic diets on metabolic outcomes, diet adherence, and sustainability in adults with overweight or metabolic disorders. The results of these diets were compared with control groups.