TOP-5 studies on biohacking and longevity from July 24, 2026 - July 31, 2026

The dawn phenomenon in diabetes: pathophysiology from the periphery to the central nervous system and therapeutic strategies based on circadian rhythms; Metformin and sleep health in older adults with type 2 diabetes: mechanisms, clinical data, and directions for future research, narrative review; Development of physical seed priming as a practical tool for stress-resistant agricultural crop production; Subcutaneous implantable sensors for health monitoring: applications, challenges, and new technologies; From primates to humans: mapping the host-microbiome-health relationships in aging.
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5. The dawn phenomenon in diabetes: pathophysiology from the periphery to the central nervous system and therapeutic strategies based on circadian rhythms.

Type: Review
Source: PubMed

About the work.
The article is dedicated to studying the dawn phenomenon (DP) in patients with type 2 diabetes, analyzing its pathophysiology and impact on blood glucose levels. Issues related to glucose variability and therapeutic strategies are discussed.

Results.
Patients with DP demonstrate increased mean glucose variability over 24 hours compared to those without DP. Traditional views link DP to physiological spikes in counter-regulatory hormone secretion, leading to increased glucose production in the liver and decreased sensitivity of peripheral tissues to insulin.

4. Metformin and sleep health in older adults with type 2 diabetes: mechanisms, clinical data, and directions for future research, narrative review.

Type: Review
Source: PubMed

About the work.
The review focuses on the impact of metformin on sleep quality in older adults with type 2 diabetes. Mechanisms through which metformin may improve sleep, as well as clinical data on this issue, are discussed.

Results.
Available clinical data indicate moderate improvements in sleep metrics, particularly in patients with a Pittsburgh Sleep Quality Index above 5. Rare side effects, such as vivid dreams and nightmares, occur infrequently and usually resolve with dose adjustment.

3. Development of physical seed priming as a practical tool for stress-resistant agricultural crop production.

Type: Review
Source: PubMed

About the work.
The study is dedicated to the development of physical seed priming methods to enhance stress resistance in agriculture. The mechanisms of action of physical methods and their impact on seed and seedling performance are discussed.

Results.
The available abstract describes the results insufficiently in detail.

2. Subcutaneous implantable sensors for health monitoring: applications, challenges, and new technologies.

Type: Review
Source: PubMed

About the work.
The possibilities and challenges of using subdermal sensors for health monitoring are discussed, including an analysis of current clinical devices. Key applications and issues affecting the performance of these sensors are addressed.

Results.
The available abstract describes the results insufficiently in detail.


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