TOP-5 studies on keto, low-carb diets, and intermittent fasting from June 15, 2026 - June 22, 2026

Pigmented prurigo - an increasingly diagnosed dermatological condition; Ketone metabolism at the intersection of atherosclerosis and brain dysfunction; Changes in body composition and daily energy expenditure; Integration of technology in healthcare: a review of digital interventions for obesity management in adults; Intermittent fasting and cardiometabolic responses to cardiac stress: a systematic review of preclinical studies.
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5. Integration of technology in healthcare: a review of digital interventions for obesity management in adults.

Type: Systematic review / meta-analysis
Source: PubMed

About the work.
The aim of the study was to map existing digital interventions for obesity management in adults, describing their characteristics and outcomes. The study covered various models of digital interventions and their application in different settings.

Results.
The included studies showed diverse and inconsistently presented results, some of which demonstrated significant weight loss, improvement in metabolic parameters, and behavioral outcomes, including diet adherence, physical activity, and self-monitoring, as well as favorable results regarding feasibility and potential for continuity of service delivery during the COVID-19 pandemic.

4. Pigmented prurigo - an increasingly diagnosed dermatological condition associated with the ketogenic diet.

Type: Review
Source: PubMed

About the work.
The study focuses on a rare inflammatory dermatosis - pigmented prurigo, which is observed in adults of various ethnic backgrounds and is associated with ketogenic diets. Cases are discussed where the condition arose in the context of fasting or limited carbohydrate intake.

Results.
In all cases, treatment with doxycycline led to a rapid resolution of all skin rashes.

3. Ketone metabolism at the intersection of atherosclerosis and brain dysfunction.

Type: Review
Source: PubMed

About the work.
The study aims to explore the role of ketone bodies in metabolism and their impact on atherosclerosis and brain dysfunction. Mechanisms through which ketones may improve endothelial function and reduce inflammation are discussed.

Results.
Ketone bodies improve endothelial function, reduce inflammation, and promote the stability of atherosclerotic plaques. In the brain, they serve as alternative energy substrates and enhance synaptic resilience.

2. Changes in body composition and daily energy expenditure six and twelve months after a very low-calorie ketogenic diet.

Type: Journal article
Source: PubMed

About the work.
The study aims to assess changes in body composition and daily energy metabolism in women with obesity six and twelve months after starting a very low-calorie ketogenic diet. The study involved 17 women who underwent a 1-month diet followed by a transition phase.

Results.
After an initial weight loss of 7%, body mass further decreased by 3.9% at six months, and a decrease of 2.4% was observed at twelve months.


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