TOP-5 Studies on Keto, Low-Carbohydrate Diets, and Intermittent Fasting from 03.08.2026 - 10.08.2026
Impact on liver health: systematic review and meta-analysis; Effectiveness and safety of therapy in adolescents and adults with drug-resistant epilepsy: systematic review and meta-analysis; Impact of low-carbohydrate diets, including intermittent fasting, on body weight, glycemic levels, and quality of life in adults with type 1 diabetes and overweight/obesity; Impact of 8-hour time-restricted eating (16/8 TRE) on glucose metabolism and lipid profile in adults: systematic review and meta-analysis; Impact of intermittent fasting on hepatic steatosis in metabolic dysfunction associated with fatty liver.
5. Impact of 8-hour time-restricted eating (16/8 TRE) on glucose metabolism and lipid profile in adults: systematic review and meta-analysis.
About the study.
The study aimed to assess the impact of time-restricted eating (16/8 TRE) on glycolipid metabolism in adults compared to a control diet. The analysis included 23 randomized controlled trials involving 1280 participants.
Results.
16/8 TRE led to a slight reduction in fasting glucose levels, HOMA-IR, and insulin. A moderate effect on HDL cholesterol levels was also observed. Significant improvements in triglyceride and LDL cholesterol levels were noted in men. Participants with higher levels of physical activity showed greater improvements in LDL cholesterol levels.
4. Impact of ketogenic diet on liver health: systematic review and meta-analysis.
About the study.
The study aimed to evaluate the impact of the ketogenic diet on liver health based on a systematic review and meta-analysis of randomized controlled trials.
Results.
The ketogenic diet significantly reduces levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and alkaline phosphatase (ALP), but does not significantly affect liver fibrosis. Furthermore, a diet followed for less than 12 weeks leads to a greater reduction in liver enzyme levels in individuals with a BMI of less than 30.
3. Effectiveness and safety of ketogenic diet therapy in adolescents and adults with drug-resistant epilepsy: systematic review and meta-analysis.
About the study.
The study aimed to assess the effectiveness and safety of the ketogenic diet (KD) in adolescents and adults with drug-resistant epilepsy. Data on seizure frequency reduction and other aspects related to the use of KD were analyzed in the systematic review and meta-analysis.
Results.
The overall proportion of patients with a reduction in seizure frequency of more than 50% was 42.82%. A positive effect of KD was observed in 53.4% of patients with generalized DR, while 14.4% with focal DR. KD was safe and generally well tolerated.
2. Impact of low-carbohydrate diets, including intermittent fasting, on body weight, glycemia, and quality of life in adults with type 1 diabetes and overweight/obesity: systematic review.
About the study.
The aim of this systematic review was to evaluate the effectiveness and safety of low-carbohydrate diets, including intermittent fasting, in adults with type 1 diabetes and overweight or obesity. The effects of eucaloric and hypocaloric low-carbohydrate diets on body weight, glycemia, and quality of life were compared.