TOP-5 studies on keto, low-carb diets, and intermittent fasting from 29.06.2026 - 06.07.2026
Chances for neuroprotection: ketogenic diet and Parkinson's disease; The impact of lipid composition on anxiety-like behavior and the neurometabolic profile in healthy rats; The effect of early time-restricted feeding on a Mediterranean diet compared to naltrexone/bupropion on liver fibrosis in individuals with cardiometabolic risk factors in an outpatient clinic: study protocol for a randomized controlled trial (MEDFAST study); Intermittent fasting for diabetes treatment: time to update clinical guidelines; Time-restricted feeding and muscle aging: research progress from molecular mechanisms to personalized intervention strategies.
5. The effect of early time-restricted feeding on a Mediterranean diet compared to naltrexone/bupropion on liver fibrosis in individuals with cardiometabolic risk factors in an outpatient clinic: study protocol for a randomized controlled trial (MEDFAST study).
About the work.
The study aims to compare the effects of early time-restricted feeding in a Mediterranean style and treatment with naltrexone/bupropion on liver fibrosis in individuals with cardiometabolic risk factors. The study involves adults with overweight and moderate to severe liver fibrosis.
Results.
The available abstract does not describe the results in sufficient detail.
4. Intermittent fasting for diabetes treatment: time to update clinical guidelines.
About the work.
The aim of the study was to assess the effectiveness of intermittent fasting in diabetes treatment based on clinical trial data. Various types of intermittent fasting and their impact on patients with type 2 diabetes, prediabetes, and other forms of diabetes were considered.
Results.
Intermittent fasting reduces HbA levels by 0.3-1.2%, fasting glucose levels, 24-hour glucose levels, and body weight compared to regular eating patterns. It is as effective as calorie restriction for improving glycemic control and does not increase the risk of hypoglycemia when adjusting medications.
3. Fat chance for neuroprotection: ketogenic diet and Parkinson's disease.
About the work.
This literature review focuses on the role of the ketogenic diet in managing Parkinson's disease, including its effects on symptoms and disease progression.
Results.
Preliminary data suggest that the ketogenic diet may provide symptomatic benefits in Parkinson's disease, particularly for non-motor symptoms such as urinary function, fatigue, and cognitive functions, although consistent improvement in motor outcomes has not yet been demonstrated.
2. The impact of lipid composition of the ketogenic diet on anxiety-like behavior and the neurometabolic profile in healthy rats.
About the work.
The study aimed to investigate the impact of lipid composition of the ketogenic diet on behavior and the neurometabolic profile in healthy rats. The effects of a classic ketogenic diet and a modified ketogenic diet enriched with polyunsaturated fatty acids were compared.
Results.
The classic ketogenic diet induced anxiety-like behavior in rats, evidenced by a decrease in the number of entries into open sections and an increase in time spent in closed sections, while the modified ketogenic diet did not induce such effects, maintaining behavioral parameters at the level of the control group.