TOP-5 Studies on Obesity, Diabetes, and Insulin Resistance from September 15, 2026 to September 22, 2026
Comparative effects of ketogenic diets and Mediterranean diets on obesity and metabolic outcomes: a systematic review and meta-analysis; Artemisinin and its derivatives in metabolic syndrome: from multi-target mechanisms to translational opportunities (Review); Epigenetic determinants of GLP-1 sensitivity: integrating dietary modulation beyond genetics; Nutritional transitions, obesity, and type 2 diabetes in the Middle East and North Africa; Gut microbiota: a new key role in stone formation - from oxalate metabolism to systemic regulation.
5. Artemisinin and its derivatives in metabolic syndrome: from multi-target mechanisms to translational opportunities (Review).
About the work.
The review focuses on investigating the potential of artemisinin and its derivatives in treating metabolic syndrome, including their mechanisms of action and clinical application possibilities.
Results.
The available abstract does not describe the results in sufficient detail.
4. Comparative effects of ketogenic and Mediterranean diets on obesity and metabolic outcomes: a systematic review and meta-analysis.
About the work.
The aim of this study was to compare the effects of ketogenic and Mediterranean diets on anthropometric and metabolic parameters in adults. The study included randomized controlled trials comparing these two diets.
Results.
The ketogenic diet significantly reduced body weight by 3.56 kg, body mass index by 1.86 kg/m², waist circumference by 4.25 cm, percentage of total fat by 2.09%, and insulin levels by 3.15 µU/ml compared to the Mediterranean diet. A significant reduction in total cholesterol by 9.71 mg/dl was also observed with the ketogenic diet.
3. Epigenetic determinants of GLP-1 sensitivity: integrating dietary modification beyond genetics.
About the work.
The review discusses epigenetic mechanisms related to diet and their impact on the body's response to GLP-1 receptor agonists. Genetic factors and limitations, as well as diet-dependent regulatory mechanisms that may influence metabolic outcomes, are discussed.
Results.
The available abstract does not describe the results in sufficient detail.
2. Nutritional transitions, obesity, and type 2 diabetes in the Middle East and North Africa.
About the work.
A review of the epidemiological situation of obesity and type 2 diabetes in Middle Eastern and North African countries, including an analysis of risk factors and shortcomings in research and policy.
Results.
Despite worsening trends, the overall picture, including the burden of disease and its causes, remains underexplored. A high prevalence of obesity and type 2 diabetes is observed in Gulf countries, while sharp increases in body mass index and plasma glucose levels are recorded in North Africa. These epidemics impose a significant and underestimated economic burden.