TOP-5 Studies on Disease Treatment from 16.08.2026 - 23.08.2026

Analysis of the sensitive period of body mass index in adulthood and cancer risk: a meta-analysis of individual participant data from over 720,000 participants in the ABACus 2 consortium; The impact of short-term reduction of hepatic triglycerides on vascular health in adults with metabolic dysfunction associated with fatty liver or at risk; A metabolic revolution in dermatology: obesity, insulin resistance, and ultra-processed diets as factors of skin inflammation; Evaluation of the impact of the Ripe for Revival mobile market with vouchers on food security, fruit and vegetable consumption, and blood pressure in rural areas of eastern North Carolina: a study protocol with a quasi-experimental design; Nutrition and management of chronic diseases for clinical endocrinologists: using a chronic disease model based on undernutrition.
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5. Analysis of the sensitive period of body mass index in adulthood and cancer risk: a meta-analysis of individual participant data from over 720,000 participants in the ABACus 2 consortium.

Type: Systematic review / meta-analysis
Source: PubMed

About the work.
The study aims to analyze the impact of body mass index (BMI) on the risk of developing cancer at different age periods of adult life. Data from over 720,000 participants were used to identify sensitive age periods for cancer risk associated with obesity.

Results.
Positive associations between BMI and obesity-related cancer were found in the age range of 30-65 years. In women aged 35 and 40 years, interactions with obesity-related cancer risk were identified, with HRs of 1.04 and 1.05, respectively. Higher BMI increased the risk of obesity-related cancer throughout adult life.

4. The impact of short-term reduction of hepatic triglycerides on vascular health in adults with metabolic dysfunction or at risk of steatogenic liver disease.

Type: Randomized controlled trial
Source: PubMed

About the work.
The study aims to assess the impact of short-term reduction of liver triglyceride levels on vascular health in adults with metabolic syndrome. Participants were divided into two groups and subjected to dietary intervention.

Results.
The reduction in liver triglyceride levels was 15% relative to baseline. Improvements in vascular function and reduced cardiovascular risk were observed after two weeks of dietary intervention.

3. A metabolic revolution in dermatology: obesity, insulin resistance, and ultra-processed diets as factors of skin inflammation.

Type: Review
Source: PubMed

About the work.
The study links inflammatory dermatoses with metabolic factors such as obesity and insulin resistance, as well as the impact of ultra-processed diets on the skin.

Results.
High fast food consumption is associated with an increased risk of severe atopic dermatitis in children. Nutritional factors correlate with worsening skin diseases, and dietary changes may help reduce skin inflammation in some patients.

2. Evaluation of the impact of the Ripe for Revival mobile market with vouchers on food security, fruit and vegetable consumption, and blood pressure in rural areas of eastern North Carolina: a study protocol with a quasi-experimental design.

Type: Clinical study
Source: PubMed

About the work.
The aim of the study is to assess the impact of the Ripe for Revival mobile market using vouchers on fruit and vegetable consumption, as well as on food security in rural areas of North Carolina. The study includes a comparison of consumption and health indicators among program participants.

Results.
The available abstract describes the results insufficiently.


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