How to protect yourself from body intoxication.

The ketogenic diet creates metabolic conditions in the body where detoxification organs (liver, kidneys, intestines) work more efficiently, and the level of systemic inflammation and oxidative stress decreases. This explains why people on a keto diet objectively cope more easily with various forms of toxicosis—from food intoxication to the consequences of inflammatory diseases.

Ketones as Clean Fuel

In a state of ketosis, the body uses ketone bodies (beta-hydroxybutyrate, acetoacetate) instead of glucose. This "clean" fuel produces fewer free radicals upon oxidation compared to glucose. This reduces oxidative stress—one of the key factors in the development of toxicosis and inflammatory conditions.

Increased Activity of the Glutathione Pathway

The ketogenic diet promotes the activation of the NRF2 pathway—the main regulator of antioxidant defense. This increases the synthesis of glutathione, which is the primary intracellular antioxidant and participates in the neutralization of xenobiotics (drugs, chemicals, toxins).

Reduction of Inflammatory Processes

Ketosis lowers the levels of pro-inflammatory cytokines (such as TNF-α and IL-6), which often increase during intoxication. Thus, systemic inflammation, which exacerbates toxicosis, is reduced.

Optimization of Liver Function

The liver is the main detoxification organ. With ketogenic nutrition, its function improves due to:

• reduced fat infiltration (especially in non-alcoholic fatty liver disease),
• lower levels of insulin and leptin (which reduces the burden on the liver),
• activation of autophagy—a process in which cells recycle damaged structures and toxins.

Provision of Amino Acids and Cofactors

The ketogenic diet is rich in proteins and fats that contain important amino acids (such as cysteine, glycine), necessary for glutathione synthesis.

Fats also provide phospholipids and fat-soluble vitamins (A, D, E, K), which participate in protecting cell membranes from toxins.

Stabilization of Blood Sugar

High levels of glucose enhance the glycation of proteins and the formation of advanced glycation end products (AGEs), which are toxic in themselves. Keto stabilizes blood sugar levels, reducing this type of endogenous intoxication.