Rebaudioside M — a highly purified glycoside of stevia, characterized by pronounced sweetness and minimal impact on glycemia. Unlike classic sugar, rebaudioside M does not raise glucose and insulin levels, making it sought after in low-carbohydrate and diabetic diets.
Against the backdrop of rising metabolic disorders and interest in reducing sugar consumption, it is viewed as one of the most promising natural sweeteners.
Modern technologies allow for the production of rebaudioside M both through extraction from stevia leaves and using biofermentation. This ensures a high degree of purification and a more neutral taste compared to earlier forms of steviol glycosides.
History and Origin
Rebaudioside M is extracted from the plant Stevia rebaudiana, which grows in South America. The leaves of stevia have traditionally been used by local populations to sweeten beverages long before the advent of industrial sugar.
Active research on individual stevia glycosides began in the late 20th century. Rebaudioside M was identified as one of the sweetest and organoleptically mild components. Its flavor profile is characterized by less bitterness compared to rebaudioside A, which increased interest from the food industry.
Today, rebaudioside M is approved for use in several countries as a safe sweetener within the acceptable daily intake of steviol glycosides.
Chemical Structure and Properties
Rebaudioside M belongs to the group of steviol glycosides — compounds composed of the aglycone steviol and several glucose molecules. Its complex glycosidic structure determines its intense sweetness and heat stability.
Main properties:
- 200–300 times sweeter than sucrose;
- contains no calories in physiologically significant amounts;
- thermostable and resistant to a wide range of pH;
- does not raise blood glucose and insulin levels;
- has a milder flavor profile compared to other stevia glycosides.
After consumption, steviol glycosides are metabolized by the intestinal microbiota to steviol, which is then excreted from the body.
Application in Nutrition
Rebaudioside M is used in the production of beverages, desserts, protein bars, dairy alternatives, and functional products. Due to its high sweetness, it allows for a significant reduction in sugar content without compromising taste.
In low-carbohydrate and keto diets, rebaudioside M is used for:
- sweeter beverages without exiting ketosis;
- baking with minimal carbohydrate load;
- creating desserts without glycemic spikes.
Potential Health Benefits
The main advantage of rebaudioside M is its neutral impact on carbohydrate metabolism. This makes it suitable for people with diabetes, insulin resistance, and metabolic syndrome.
Research also considers the following effects:
- support for glycemic control;
- possible moderate influence on blood pressure;
- reduction of overall caloric intake when replacing sugar.
It is important to consider the acceptable daily intake of steviol glycosides, calculated based on body weight.
Rebaudioside M represents a modern solution for reducing sugar in the diet without losing sweetness. Its use is particularly relevant in the context of preventing metabolic disorders and developing low-carbohydrate dietary strategies.







