L-carnitine — is a substance involved in fat metabolism, particularly important for energy production in cells.
It is synthesized in the body from the amino acids lysine and methionine and additionally obtained from food — primarily from meat products.
Its main function — is the transportation of long-chain fatty acids into the mitochondria, where they are oxidized to produce energy. This makes L-carnitine important for people leading an active lifestyle, aiming to improve endurance, recover after workouts, and effectively use fats as fuel.
Beneficial Properties
- participates in the transport of fatty acids into the mitochondria;
- increases the energy potential of the body;
- helps reduce levels of triglycerides and LDL cholesterol;
- supports the cardiovascular system;
- reduces muscle fatigue and accelerates recovery after exertion.
Daily Requirement and Sources
The recommended daily dose of L-carnitine is:
- for most adults — 500–2000 mg per day;
- with increased physical activity — up to 3000 mg under specialist supervision.
L-carnitine is primarily obtained from animal food. Major sources include:
- red meat (especially lamb and beef);
- fish and poultry;
- dairy products.
Vegetarians and people with impaired L-carnitine synthesis (for example, due to liver or kidney diseases) may experience a deficiency and need supplements.
Symptoms and Consequences of Deficiency
- general fatigue and decreased endurance;
- accumulation of fat deposits due to disrupted lipid metabolism;
- problems with recovery after physical exertion;
- possible disturbances in heart and muscle function;
- disruption of energy metabolism at the cellular level.
Deficiency can develop due to congenital metabolic disorders, kidney and liver diseases, strict diets, or vegan nutrition.
Possible Risks of Excess and Their Manifestations
Although L-carnitine is generally well tolerated, its excess may cause:
- digestive disorders (nausea, diarrhea);
- unpleasant body and breath odor (fishy smell);
- increased levels of TMAO — a compound associated with an increased risk of atherosclerosis;
- headaches and insomnia with prolonged high-dose use.
The acceptable upper limit of intake is up to 3000 mg per day. Exceeding this dose may lead to side effects, especially with prolonged use without medical supervision.