Myristic acid (Saturated)

May participate in regulating cholesterol levels. In excess, it may increase LDL cholesterol levels, which is associated with the risk of cardiovascular diseases.
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Myristic acid is a saturated fatty acid containing 14 carbon atoms.

The main sources of myristic acid include:

Myristic acid plays an important role in human metabolism, participating in lipid synthesis and maintaining cellular structure. It contributes to the formation of cell membranes and is a source of energy.

Additionally, myristic acid influences the immune system, helping the body fight infections and inflammation.

Its presence in the diet may improve overall health and strengthen the body’s protective functions.

Daily Dose of Myristic Acid

The recommended daily dose of myristic acid is not established; however, many experts advise limiting saturated fat intake to 10% of total caloric intake.

This is approximately 20 g for an adult with normal weight.

Possible forms and their learnability

Nutrient forms are listed from best to worst:

Free myristic acid. It is found in some food products and can be absorbed directly through the intestines. However, excessive consumption is associated with increased levels of total cholesterol and low-density lipoproteins (LDL), which may increase the risk of cardiovascular diseases.
Triglycerides containing myristic acid. In this form, myristic acid is bound to glycerol and is part of the fats found in food. After consumption, such triglycerides are broken down in the intestine into free fatty acids and monoglycerides, which are then absorbed.
Myristoilated proteins. In the body, myristic acid can covalently attach to the N-terminal glycine of certain proteins in a process known as myristoylation. This modification plays an important role in membrane attachment and functional activity of various signaling proteins.
Myristic acid-based nanoparticles. Used in pharmaceuticals to improve the bioavailability of certain drugs. For example, solid lipid nanoparticles containing myristic acid have been developed to enhance the oral absorption and therapeutic efficacy of rifaximin against MRSA-induced pneumonia.

Deficiency of Myristic Acid

A deficiency of myristic acid may lead to impaired fat metabolism, which in turn can cause weight and energy level issues.

A lack of this nutrient may also result in:

  • decreased immune function;
  • worsening skin condition.

Excess of Myristic Acid

Primarily, an excess of myristic acid can raise blood lipid levels, increasing the risk of cardiovascular diseases.

Moreover, excessive consumption of this acid may contribute to the development of inflammatory processes in the body, negatively affecting overall health.


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Fatty Acids
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