Alpha-linolenic acid (Omega-3)

Maintaining heart and brain health, reducing inflammation. A deficiency increases the risk of cardiovascular diseases, inflammatory processes, and cognitive function deterioration.
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Alpha-linolenic acid (ALA) is an essential omega-3 fatty acid that plays a key role in maintaining human health.

It is an important building block for the production of long-chain polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are necessary for the normal functioning of the brain and cardiovascular system.

As an essential acid, ALA must be obtained from food, as the human body is unable to synthesize it on its own.

Alpha-linolenic acid (ALA) plays a crucial role in brain function, participates in the formation of cell membranes, and influences the functioning of many body systems.

To maintain health, it is recommended to consume foods rich in this acid, such as flaxseeds, chia seeds, and walnuts.

Diagram of sources of alpha-linolenic acid in the diet.
Diagram of sources of alpha-linolenic acid in the diet.

Health Benefits

Heart health. Studies show that consumption of alpha-linolenic acid may help reduce the risk of cardiovascular diseases by improving cholesterol levels and reducing inflammation.

Brain function. Alpha-linolenic acid plays a key role in maintaining cognitive functions and may be associated with a reduced risk of neurodegenerative diseases.

Skin benefits. Alpha-linolenic acid may improve skin health by promoting hydration and reducing inflammatory processes.

Mood. Some studies link the consumption of alpha-linolenic acid with improved mood and reduced symptoms of depression.

Inflammation. It has anti-inflammatory properties and may help treat various inflammatory diseases, such as arthritis.

Cholesterol levels. Consumption of alpha-linolenic acid may help lower total cholesterol and low-density lipoprotein (LDL) levels in the blood.

Pregnancy. Studies show that adequate intake of alpha-linolenic acid during pregnancy may support maternal health and fetal brain development.

Aging. It may slow down the aging processes by improving cell health and reducing oxidative stress.

Blood sugar levels. Some data suggest that alpha-linolenic acid may help improve blood sugar control in people with diabetes.

Daily Requirement for Alpha-Linolenic Acid

The daily requirement for alpha-linolenic acid (ALA) for adults is approximately 1.1-1.6 grams per day. This amount helps maintain normal body function and prevents the development of deficiency.

For pregnant women the requirement is slightly higher due to the importance of ALA for fetal brain development.

Possible forms and their learnability

Nutrient forms are listed from best to worst:

ALA in the composition of triglycerides of vegetable oils. The most natural form is found in flaxseeds, chia seeds, hemp, and walnuts. It is absorbed in the body through standard fat digestion mechanisms involving bile and lipases. Advantages include natural form, good tolerance, and high antioxidant value when freshly cold-pressed. Disadvantages include rapid oxidation (especially in ground seeds and unprotected oils).
ALA in encapsulated oils (softgel). Oil forms (more often flaxseed, less often chia or perilla) enclosed in capsules. The advantage is protection from oxidation, precise dosage, and ease of use. The downside is that the cost is higher than that of oil in a bottle. The absorption rate is similar to that of oil, but the stability is better.

Options on iHerb:

California Gold Nutrition, Alpha Lipoic Acid, 600 mg, 120 Veggie Capsules
California-Gold-Nutrition,-Alpha-Lipoic-Acid,-600-mg,-120-Veggie-Capsules
California Gold Nutrition, Alpha Lipoic Acid, 600 mg, 120 Veggie Capsules
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ALA in the composition of complex supplements (omega-3-6-9 blends). ALA is found in combined preparations where omega-6 and omega-9 are present together. Plus - a wide range of fatty acids. Minus - competition for desaturation enzymes: an excess of omega-6 may reduce the conversion of ALA to EPA/DHA. It is used more as a general health support than as a specific source of omega-3.
ALA in modified forms (esters, emulsions). Sometimes ALA is introduced in the form of ethyl esters or microemulsions to enhance bioavailability. Such forms are less common but theoretically provide better absorption in cases of bile secretion issues. However, there is less clinical evidence specifically for ALA than for EPA/DHA.

Symptoms and Consequences of Deficiency

Symptoms of ALA deficiency may include dry skin, brittle nails, hair problems, vision deterioration, arterial stiffness, and an increased risk of inflammatory diseases. These signs may indicate insufficient intake of omega-3 fatty acids in general.

Prolonged ALA deficiency may lead to serious health consequences, including impaired brain development and decreased cognitive functions.

Potential Risks of Excess and Their Prevention

Although ALA is an important omega-3 fatty acid, excessive intake may increase the risk of blood clot formation, which can potentially lead to cardiovascular diseases.

It may also worsen the body’s anti-inflammatory responses, as excess ALA can disrupt the balance with other essential fatty acids.

Interesting Facts About Alpha-Linolenic Acid

Consumption by vegetarians and vegans. Alpha-linolenic acid is an important source of omega-3 for people following a plant-based diet, as they do not obtain EPA and DHA from fish.

Evolution and discovery. Alpha-linolenic acid was first isolated in 1929, and since then it has attracted the attention of researchers due to its beneficial properties.

Animal studies. Experiments with animals have shown that alpha-linolenic acid may increase lifespan and improve health in old age.

Culinary processing. Some cooking methods may reduce ALA levels, but not all. It is better to avoid high temperatures and prolonged processing.

The most important thing about Alpha-linolenic acid (Omega-3)Watch all
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