Adipokines

Adipokines are a group of biologically active substances (proteins) produced and secreted by adipose tissue. They play an important role in regulating metabolism, inflammatory processes, and immune functions in the body. The main adipokines include leptin, adiponectin, resistin, visfatin, and others.

Adipokines participate in regulating various processes in the body:

• Appetite and energy balance control
• Insulin sensitivity regulation
• Inflammatory and immune reactions
• Lipid and glucose metabolism management

Adipokines and the Ketogenic Diet

In the context of the ketogenic diet, adipokines acquire special significance as dietary changes can affect their levels in the body.

For example, leptin, which regulates hunger and metabolic processes, may change on the ketogenic diet due to fat loss. A decrease in body fat leads to a reduction in leptin levels, which can decrease appetite.

Adiponectin, another important adipokine, improves insulin sensitivity and has anti-inflammatory properties. Studies show that adiponectin levels may increase with adherence to the ketogenic diet, potentially benefiting insulin resistance and reducing the risk of developing type 2 diabetes.